Much has changed since Elizabeth Blackwell became the first US female physician, but a lack of sponsorship still keeps women in medicine from leadership roles.

Dr Salahuddin Kazi, MD, comments on the challenges of diagnosing seronegative rheumatic diseases and discusses a case presentation that highlights these difficulties.

We spoke with Mark Richardson, MD, PhD, and John Tesser, MD, to discuss vagus nerve stimulation for the treatment RA and results of the pivotal RESET-RA trial.

J Eugene Huffstutter, MD, and Robert G Hylland, MD, discuss the evolving concept of frailty in rheumatology.

The exact definition of difficult-to-treat rheumatoid arthritis has been the subject of debate due to the heterogeneous patient population.